Dichloromethane → 3-(2-{5-[cyclopentyl(methyl)sulfamoyl]pyridin-2-yl}-3-oxo-2,3-dihydro-1H-pyrazol-4-yl)-3-phenyl-N-(2,2,2-trifluoroethyl)propanamide

HRID 188032Notes

Reaction equation

HRID 188032 reaction equation
[B-:49]([F:50])([F:51])([F:52])[F:53].[CH:1]1([N:6]([S:7](=[O:8])(=[O:9])[c:10]2[cH:11][cH:12][c:13](-[n:16]3[nH:17][cH:18][c:19]([CH:22]([CH2:23][C:24](=[O:25])[O-:26])[c:27]4[cH:28][cH:29][cH:30][cH:31][cH:32]4)[c:20]3=[O:21])[n:14][cH:15]2)[CH3:33])[CH2:2][CH2:3][CH2:4][CH2:5]1.[CH:34]([N:35]([CH2:36][CH3:37])[CH:38]([CH3:39])[CH3:40])([CH3:41])[CH3:42].[Cl:71][CH2:72][Cl:73].[F:43][C:44]([CH2:45][NH2:46])([F:47])[F:48].[n:54]1([O:55][C:56]([N:57]([CH3:58])[CH3:59])=[N+:60]([CH3:61])[CH3:62])[c:63]2[cH:64][cH:65][cH:66][cH:67][c:68]2[n:69][n:70]1>>[CH:1]1([N:6]([S:7](=[O:8])(=[O:9])[c:10]2[cH:11][cH:12][c:13](-[n:16]3[nH:17][cH:18][c:19]([CH:22]([CH2:23][C:24](=[O:26])[NH:46][CH2:45][C:44]([F:43])([F:47])[F:48])[c:27]4[cH:28][cH:29][cH:30][cH:31][cH:32]4)[c:20]3=[O:21])[n:14][cH:15]2)[CH3:33])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

7

Reactant 6

HCID 6344DichloromethaneHCID 9773Ethanamine, 2,2,2-trifluoro-HCID 26255TetrafluoroborateHCID 81531DiisopropylethylamineHCID 130500O-benzotriazol-1-yl-tetramethyluroniumHCID 86659758HCID 86659758, compound

Product 1

HCID 674555723-(2-{5-[cyclopentyl(methyl)sulfamoyl]pyridin-2-yl}-3-oxo-2,3-dihydro-1H-pyrazol-4-yl)-3-phenyl-N-(2,2,2-trifluoroethyl)propanamide

Sources & evidence

ORD record
ord-215ab34da63c435d8cf2167a8cc38df9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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