Acetic Acid → 2-Oxopropanal isopropylhydrazone

Beteiligte Stoffe

Reaktionsschritte

To a solution of isopropylhydrazine hydrochloride (2.0 g, 18 mmol) in water (100 mL) was added acetic acid (1.7 mL) followed by the dropwise addition of pyruvaldehyde (2.6 g, 14.5 mmol) in water. The solution was stirred at room temperature overnight. The aqueous layer was extracted with CH2Cl2 (4×) and the combined organic extracts were washed with sat. aq. NaHCO3. The organic extract was dried over Na2SO4, filtered and concentrated to afford 2-oxopropanal isopropylhydrazone (1.3 g, 56%).

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