Lithium Hydroxide → HCID 58123101, compound

Participants

Reaction Steps

To a solution of ethyl 3-ethyl-7-methoxy-1-methyl-1H-indazole-5-carboxylate (52 mg, 0.20 mmol) in THF (1.5 mL) was added 1 M LiOH (0.36 mL, 0.36 mmol). The mixture was heated at reflux overnight. The reaction was cooled to room temperature, concentrated, triturated with 1 N HCl, the filtered solids were then washed with water and air dried to provide the title compound (46 mg, 94%).

Provenance & Evidence