Lithium Hydroxide → HCID 178492734, compound

Participants

Reaction Steps

To a solution of ethyl 7-methoxy-3-methyl-1H-indazole-5-carboxylate (294 mg, 1.26 mmol) in EtOH (11 mL) was added 1 M LiOH (2.5 mL). The mixture was heated at reflux for 4 hours, cooled to room temperature and concentrated. The crude material was triturated with 1 N HCl, the solids were isolated by filtration and washed with water. The solid was air dried overnight to provide the title compound (235 mg, 91%).

Provenance & Evidence