HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 188042Generated: October 31, 2026
1,4-Dioxane → 5-Chloro-N-{2-[2-(1-methyl-2-pyrrolidinyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}-2-thiophenecarboxamide
https://huagongshe.com/reaction/188042
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | 2-(2-Aminoethyl)-1-methylpyrrolidine | HCID 98388 | — |
| Reactant | 5-Chloro-N-(1,3-dioxo-1,3-dihydro-2-benzofuran-4-yl)-2-thiophenecarboxamide | HCID 11392653 | — |
| Product | 5-Chloro-N-{2-[2-(1-methyl-2-pyrrolidinyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}-2-thiophenecarboxamide | HCID 12074889 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (6/10) |
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| ORD ID | ord-5b247d39b3a6481ba4b85574b8291e40 |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (6/10) |
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