HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-2-(trifluoromethyl)benzyl bromide → HCID 178460772, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-2-(trifluoromethyl)benzyl bromide | HCID 2737576 | — |
| Reactant | Ethyl 2-[(2-amino-1,3-thiazol-5-yl)sulfanyl]-2-methylpropanoate | HCID 57481427 | — |
| Reactant | HCID 178454946 | HCID 178454946 | — |
| Product | HCID 178460772 | HCID 178460772 | — |
Reaction Steps
The compound was prepared following an analogous procedure to the one described for the synthesis of 3-{2-[3-[2-(2-chloro-benzyloxy)-ethyl]-3-(trans-4-methyl -cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-2,2-dimethyl-propionic acid using 1-bromomethyl-4-fluoro-2-trifluoromethyl-benzene and 2-(2-amino-thiazol-5-ylsulfanyl)-2-methyl-propionic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08318778B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-4165ca5754624c5ebc73fe018ae1db40 |
| Source note | uspto-grants-2012_11 |