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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1881069Generated: October 28, 2026

o-Xylyl bromide → HCID 178424282, compound

https://huagongshe.com/reaction/1881069

Reaction equation

Participants

RoleNameHCIDCharge
Reactanto-Xylyl bromideHCID 6992—
ReactantEthyl 2-[(2-amino-1,3-thiazol-5-yl)sulfanyl]-2-methylpropanoateHCID 57481427—
ReactantHCID 178454946HCID 178454946—
ProductHCID 178424282HCID 178424282—

Reaction Steps

The compound was prepared following an analogous procedure to the one described for the synthesis of 3-{2-[3-[2-(2-chloro-benzyloxy)-ethyl]-3-(trans-4-methyl -cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-2,2-dimethyl-propionic acid using 1-bromomethyl-2-methyl-benzene and 2-(2-amino-thiazol-5-ylsulfanyl)-2-methyl-propionic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08318778B2
Source datasetuspto-grants-2012_11
ORD IDord-ec859f5528bf487c964e0c4118fa2787
Source noteuspto-grants-2012_11