2-(Benzyloxy) ethanol → HCID 178496616, compound

HRID 1881123Notes

Reaction equation

HRID 1881123 reaction equation
C[C:2]([S:7][C:8]1[S:12][C:11]([NH:13][C:14]([N:16]([C@H:27]2[CH2:32][CH2:31][C@H:30](C)[CH2:29][CH2:28]2)[CH2:17][CH2:18]CCC2C=CC=CC=2)=[O:15])=[N:10][CH:9]=1)(C)[C:3]([OH:5])=[O:4].[CH3:34][O:35][C@H]1CC[C@H](N)CC1.[CH2:43]([O:50]CCO)[C:44]1[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=1>C(OC(=O)C)C>[CH2:43]([O:50][CH2:18][CH2:17][N:16]([C@H:27]1[CH2:28][CH2:29][C@H:30]([O:35][CH3:34])[CH2:31][CH2:32]1)[C:14](=[O:15])[NH:13][C:11]1[S:12][C:8]([S:7][CH2:2][C:3]([OH:5])=[O:4])=[CH:9][N:10]=1)[C:44]1[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=1

Participants

5

Reactant 3

HCID 121412-(Benzyloxy) ethanolHCID 178460760HCID 178460760, compoundHCID 178496609HCID 178496609, compound

Product 1

HCID 178496616HCID 178496616, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The compound was prepared following an analogous procedure to the one described for the synthesis of 2-Methyl-2-{2-[3-(trans-4-methyl-cyclohexyl)-3-(4-phenyl-butyl) -ureido]-thiazol-5-ylsulfanyl}-propionic acid using trans-4-methoxy-cyclohexylamine, 2-benzyloxy-ethanol and 2-aminothiazol-5-ylsulfanyl) acetic acid ethyl ester.

Workup

  1. customThe compound was prepared

Sources & evidence

ORD record
ord-2a7756460e0049f597b8a99108510b8a
Source dataset
uspto-grants-2012_11
Patent number
US08318778B2

Reaction notes

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