Sodium Hydroxide → HCID 67094222, compound

Participants

Reaction Steps

3-Chloro-5-hydroxy-6-methoxy-benzo[b]thiophene-2-carboxylic acid methyl ester (0.5 g) was dissolved in methanol (10 ml) and 5M sodium hydroxide (10 ml) added to. The solution refluxed for two hours. Methanol was evaporated and the resultant solution was acidified with 2M hydrochloric acid. The resultant solid was dried under vacuum. The product was used for the next step without any purification.

Provenance & Evidence