Potassium Carbonate → HCID 15982976, compound

HRID 1881172Notes

Reaction equation

HRID 1881172 reaction equation
[CH2:1]([N:3]([CH2:27][CH3:28])[C:4]([C:6]1[S:10][C:9]2[C:11]([N+:23]([O-:25])=[O:24])=[C:12]([O:19]C(=O)C)[C:13]([O:15]C(=O)C)=[CH:14][C:8]=2[C:7]=1[Cl:26])=[O:5])[CH3:2].C(=O)([O-])[O-].[K+].[K+]>CO.O>[CH2:27]([N:3]([CH2:1][CH3:2])[C:4]([C:6]1[S:10][C:9]2[C:11]([N+:23]([O-:25])=[O:24])=[C:12]([OH:19])[C:13]([OH:15])=[CH:14][C:8]=2[C:7]=1[Cl:26])=[O:5])[CH3:28]

Participants

5

Reactant 2

HCID 11430Potassium CarbonateHCID 67094213HCID 67094213, compound

Product 1

HCID 15982976HCID 15982976, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

5,6-Diacetoxy-3-chloro-7-nitro-benzo[b]thiophene-2-carboxylic acid diethylamide (0.32 g) was dissolved in methanol (16 ml) and a solution of potassium carbonate (0.61 g) in water (3 ml) was added to the reaction solution. It was stirred at room temperature for one hour. Methanol was evaporated and the residue was kept in cool and filtered. The solid was washed with water and recrystallized from methanol.

Workup

  1. customMethanol was evaporated
  2. temperaturein cool
  3. filtrationfiltered
  4. washThe solid was washed with water
  5. customrecrystallized from methanol

Sources & evidence

ORD record
ord-438ca10b6f684171a2f29e2a11a39f1b
Source dataset
uspto-grants-2012_11
Patent number
US08318785B2

Reaction notes

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