Nitric Acid → HCID 67094379, compound

Participants

Reaction Steps

6-Hydroxy-5-methoxy-benzo[b]thiophene-2-carboxylic acid (3.2 g) was dissolved in ethyl acetate (200 ml) and a solution of nitric acid in dichloromethane (2M, 7.7 ml) was gradually added at 0° C. into. The solution was stirred 30 min at room temperature and then it was poured into ice-cold water and filtered. The solid was washed with ethyl acetate and dried under vacuum.

Provenance & Evidence