Nitric Acid → HCID 86633440, compound

HRID 1881186Notes

Reaction equation

HRID 1881186 reaction equation
[CH2:1]([O:3][C:4]1[C:5]([OH:15])=[CH:6][C:7]([N+:12]([O-:14])=[O:13])=[C:8]([CH:11]=1)[CH:9]=[O:10])[CH3:2].[N+:16]([O-])([OH:18])=[O:17]>ClCCl>[CH2:1]([O:3][C:4]1[C:5]([OH:15])=[C:6]([N+:16]([O-:18])=[O:17])[C:7]([N+:12]([O-:14])=[O:13])=[C:8]([CH:11]=1)[CH:9]=[O:10])[CH3:2]

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 450942415-Ethoxy-4-hydroxy-2-nitrobenzaldehyde

Product 1

HCID 86633440HCID 86633440, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

5-Ethoxy-4-hydroxy-2-nitro-benzaldehyde (1.6 g) was dissolved in dichloromethane (30 ml) and a solution of nitric acid in dichloromethane (2M, 13 ml) was gradually added at a temperature under 30° C. The solution was stirred at room temperature for 10 min and then it was poured into ice-cold water. The organic phase was washed with water and then it was dried and evaporated.

Workup

  1. additionit was poured into ice-cold water
  2. washThe organic phase was washed with water
  3. customit was dried
  4. customevaporated

Sources & evidence

ORD record
ord-54c530f1a88d424cae06118e9b210021
Source dataset
uspto-grants-2012_11
Patent number
US08318785B2

Reaction notes

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