HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 67094349, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 67094460 | HCID 67094460 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 67094349 | HCID 67094349 | — |
Reaction Steps
6-Benzyloxy-5-methoxybenzofuran-2-carboxylic acid ethyl ester (7.3 g), acetic acid (45 ml) and conc. HCl (24 ml) were stirred at 50° C. for 0.5 hour. Water was added and pH adjusted to 3 with NaOH. The mixture was extracted with ethyl acetate. Ethyl acetate was dried with Na2SO4 and evaporated to dryness. The product was recrystallized from toluene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08318785B2 |
| Source dataset | uspto-grants-2012_11 |
| ORD ID | ord-547aba392768433cb61a0f4f2053ec94 |
| Source note | uspto-grants-2012_11 |