反应详情

6-Benzyloxy-5-methoxybenzofuran-2-carboxylic acid ethyl ester (7.3 g), acetic acid (45 ml) and conc. HCl (24 ml) were stirred at 50° C. for 0.5 hour. Water was added and pH adjusted to 3 with NaOH. The mixture was extracted with ethyl acetate. Ethyl acetate was dried with Na2SO4 and evaporated to dryness. The product was recrystallized from toluene.

1. extractionThe mixture was extracted with ethyl acetate
2. dry with materialEthyl acetate was dried with Na2SO4
3. customevaporated to dryness
4. customThe product was recrystallized from toluene