Hydrochloric Acid → 5,6-Dihydroxy-4-nitro-2-benzofuran-1(3H)-one

HRID 1881214Notes

Reaction equation

HRID 1881214 reaction equation
[OH:1][C:2]1[C:10]([N+:11]([O-:13])=[O:12])=[C:9]2[C:5]([C:6](=[O:14])[O:7][CH2:8]2)=[CH:4][C:3]=1[O:15]C(=O)C.Cl>CO>[OH:1][C:2]1[C:10]([N+:11]([O-:13])=[O:12])=[C:9]2[C:5](=[CH:4][C:3]=1[OH:15])[C:6](=[O:14])[O:7][CH2:8]2

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 67094449HCID 67094449, compound

Product 1

HCID 159832315,6-Dihydroxy-4-nitro-2-benzofuran-1(3H)-one

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Acetic acid 6-hydroxy-7-nitro-3-oxo-1,3-dihydro-isobenzofuran-5-yl ester (4.1 g) was suspended in methanol (150 ml) and 37% HCl (20 ml) followed by stirring at room temperature for 3 days. The precipitate was filtered and washed with methanol.

Workup

  1. filtrationThe precipitate was filtered
  2. washwashed with methanol

Sources & evidence

ORD record
ord-4fd535e067f3479aa52e55b56c488971
Source dataset
uspto-grants-2012_11
Patent number
US08318785B2

Reaction notes

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