反应详情

温度

40 °C

A 2 litre round bottom flask was set up with overhead stirrer, thermometer, charging funnel and condenser. 405.5 g of propiconazole (technical grade) was charged, with 400 ml of ethanol. The propiconazole solution was agitated for 30 minutes at 40° C. until solubilised. 111.76 g of 4,4′-dihydroxybiphenyl was then added. The reaction mixture was heated to 40° C. Upon heating the 4,4′-dihydroxybiphenyl dissolves to form a clear solution and crystallisation ensues with the formation of a white precipitate. The reaction mixture was agitated for 1 hour at 40° C. and subsequently cooled to 5° C. The solids were isolated by filtration on Buchner apparatus and allowed to dry in air.

1. customA 2 litre round bottom flask was set up with overhead stirrer
2. dissolutiondissolves
3. customto form
4. customa clear solution and crystallisation ensues with the formation of a white precipitate
5. temperaturesubsequently cooled to 5° C
6. customThe solids were isolated by filtration on Buchner apparatus
7. customto dry in air