Acetic acid 4-acetyl-2-(3,4-dichlorophenyl)thiophen-3-yl ester → 4-{1-[4-Acetoxy-5-(3,4-dichlorophenyl)thiphen-3-yl]ethylidenehydrazinocarbonyl}-2-nitrobenzoic acid
Reaction equation
[C:1]([C:4]1[C:5]([O:17][C:18](=[O:20])[CH3:19])=[C:6]([C:9]2[CH:14]=[CH:13][C:12]([Cl:15])=[C:11]([Cl:16])[CH:10]=2)[S:7][CH:8]=1)(=O)[CH3:2].[NH:21]([C:23]([C:25]1[CH:33]=[CH:32][C:28]([C:29]([OH:31])=[O:30])=[C:27]([N+:34]([O-:36])=[O:35])[CH:26]=1)=[O:24])[NH2:22]>>[C:18]([O:17][C:5]1[C:4]([C:1](=[N:22][NH:21][C:23]([C:25]2[CH:33]=[CH:32][C:28]([C:29]([OH:31])=[O:30])=[C:27]([N+:34]([O-:36])=[O:35])[CH:26]=2)=[O:24])[CH3:2])=[CH:8][S:7][C:6]=1[C:9]1[CH:14]=[CH:13][C:12]([Cl:15])=[C:11]([Cl:16])[CH:10]=1)(=[O:20])[CH3:19]Participants
3
Procedure
The title compound was prepared from acetic acid 4-acetyl-2-(3,4-dichlorophenyl)thiophen-3-yl ester (39.5 mg, 0.12 mmol) and 4-hydrazinocarbonyl-2-nitrobenzoic acid (40.5 mg, 0.18 mmol) following the procedure described in the synthetic example 185.
Sources & evidence
- ORD record
- ord-b25cf7b02bd84e05b3a07667cfef1a7f
- Source dataset
- uspto-grants-2012_11
- Patent number
- US08318796B2
Reaction notes
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