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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1882236Generated: November 1, 2026

5-Iodo-3-methyl-9H-pyrido[2,3-b]indole-7-carbonitrile → 5-Iodo-3-methyl-9H-pyrido[2,3-b]indole-7-carboxylic acid methyl ester

https://huagongshe.com/reaction/1882236

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Iodo-3-methyl-9H-pyrido[2,3-b]indole-7-carbonitrileHCID 16124312—
Reactant5-Amino-3-methyl-9H-pyrido[2,3-b]indole-7-carboxylic acid methyl esterHCID 58880122—
Product5-Iodo-3-methyl-9H-pyrido[2,3-b]indole-7-carboxylic acid methyl esterHCID 5937876269%

Reaction Steps

The title compound was prepared in 69% yield from Compound 130 according to the procedure outlined for the preparation of Compound 125. MS (ES) [m+H] calc'd for C14H11IN2O2, 367; found 367.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08318939B2
Source datasetuspto-grants-2012_11
ORD IDord-0a9ef38de1d343b892f4b13d47128eb7
Source noteuspto-grants-2012_11