HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propargyl bromide → 1-(Prop-2-yn-1-yl)pyrrolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propargyl bromide | HCID 7842 | — |
| Reactant | 2-Pyrrolidone | HCID 12025 | — |
| Product | 1-(Prop-2-yn-1-yl)pyrrolidin-2-one | HCID 12464313 | 58% |
Reaction Steps
As in Example 6, 15 g (0.18 mol) of 2-pyrrolidinone and 18.65 mL (1 equivalent) of propargyl bromide were reacted, then distilled in vacuo (66˜71° C./0.1 mmHg) to obtain 11.94 g (58% yield) of 1-propargyl pyrrolidin-2-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06759419B2 |
| Source dataset | uspto-grants-2004_07 |
| ORD ID | ord-f943f177f41245a6b2cd922fc0b05cdd |
| Source note | uspto-grants-2004_07 |