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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1883126Generated: November 2, 2026

1H-Indole-2-carboxylic acid, 1-methyl- → HCID 60083633, compound

https://huagongshe.com/reaction/1883126

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Indole-2-carboxylic acid, 1-methyl-HCID 27695—
Reactant2-Aminocycloheptanecarboxylic acidHCID 4083418—
ReactantAminoacetonitrile hydrochlorideHCID 11491918—
ProductHCID 60083633HCID 60083633—

Reaction Steps

2-[(1-Methyl-1H-indole-2-carbonyl)-amino]-cycloheptanecarboxylic was prepared from 2-Aminocycloheptanecarboxylic acid (Tyger Scientific Inc., Princeton N.J.) using the procedure of Example). 1-Methyl-1H-indole-2-carboxylic acid and aminoacetonitrile hydrochloride were coupled as described in Example 1 to yield 1-Methyl-1H-indole-2-carboxylic acid [(1S,2R)-2-(cyanomethyl-carbamoyl)-cycloheptyl]-amide (compound 98).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06759428B2
Source datasetuspto-grants-2004_07
ORD IDord-90c505fa1254446f8ad18170b85d65b0
Source noteuspto-grants-2004_07