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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1883134Generated: October 31, 2026

Methyl 6-bromo-1-methyl-1H-indole-2-carboxylate → 1-methyl-6-phenyl-1H-indole-2-carboxylic acid

https://huagongshe.com/reaction/1883134

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 6-bromo-1-methyl-1H-indole-2-carboxylateHCID 4777911—
Reactant6-Phenyl-1H-indole-2-carboxylic acid [(1S,2R)-2-((S)-1-cyano-3-methyl-butylcarbamoyl)-cyclohexyl]-amideHCID 20740260—
Product1-methyl-6-phenyl-1H-indole-2-carboxylic acidHCID 23510274—

Reaction Steps

Similarly, 1-methyl-6-phenyl-1H-indole-2-carboxylic acid was prepared from 6-bromo-1-methyl-1H-indole-2-carboxylic acid methyl ester and was used to prepare 6-Phenyl-1H-indole-2-carboxylic acid [(1S,2R)-2-((S)-1-cyano-3-methyl-butylcarbamoyl)-cyclohexyl]-amide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06759428B2
Source datasetuspto-grants-2004_07
ORD IDord-7e9132570fe1407db72e9335e4c795ae
Source noteuspto-grants-2004_07