反应详情

(3-Bromo-propoxy)-triisopropyl-silane (prepared from the corresponding alcohol, Greene, T. W. Protective Groups in Organic Chemistry; John Wiley & Sons, Inc.: New York, 1991) was reacted with 1H-indole-2-carboxylic acid methyl ester using procedures similar to Example 11 to give 1-(3-triisopropylsilanyloxy-propyl)-1H-indole-2-carboxylic acid as a white solid.