HuagongsheHuagongshe Chemistry Print Report · For research reference only
Semicarbazide hydrochloride → HCID 86591899, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Semicarbazide hydrochloride | HCID 11236 | — |
| Reactant | Potassium Acetate | HCID 517044 | — |
| Reactant | HCID 20740262 | HCID 20740262 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86591899 | HCID 86591899 | — |
Reaction Steps
7-Acetyl-1H-indole-2-carboxylic acid [(1S,2R)-2-(cyanomethylcarbamoyl)-cyclohexyl]-amide was reacted with potassium acetate and semicarbazide hydrochloride in methanol and purified by preparative TLC plate to yield 7-[1-(carbamoyl-hydrazono)-ethyl]-1H-indole-2-carboxylic acid [(1S,2R)-2-(cyanomethylcarbamoyl)cyclohexyl]-amide MS: 367 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06759428B2 |
| Source dataset | uspto-grants-2004_07 |
| ORD ID | ord-3e89db3ec1f441bdb11fe5f064973dd0 |
| Source note | uspto-grants-2004_07 |