HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178513294, compound → HCID 69759432, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178513294 | HCID 178513294 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 69759432 | HCID 69759432 | 130.7% |
Reaction Steps
3-[4-(N-Hydroxycarbamimidoyl)-phenyl]-2-(3-trifluoromethyl-phenyl)-propionic acid (680 mg, 1.93 mmol) was hydrogenated in acetic acid (50 ml) using palladium/charcoal (10%) as the catalyst. After two days, the catalyst was filtered off and the solvent evaporated in vacuo to give 500 mg of the desired product (65%). MS m/z: 337.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06759420B1 |
| Source dataset | uspto-grants-2004_07 |
| ORD ID | ord-dafdbf0dbb694e13bc2d3cb725d2cbbc |
| Source note | uspto-grants-2004_07 |