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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1883502Generated: November 1, 2026

HCID 178513294, compound → HCID 69759432, compound

https://huagongshe.com/reaction/1883502

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178513294HCID 178513294—
CatalystPalladiumHCID 23938—
SolventAcetic AcidHCID 176—
ProductHCID 69759432HCID 69759432130.7%

Reaction Steps

3-[4-(N-Hydroxycarbamimidoyl)-phenyl]-2-(3-trifluoromethyl-phenyl)-propionic acid (680 mg, 1.93 mmol) was hydrogenated in acetic acid (50 ml) using palladium/charcoal (10%) as the catalyst. After two days, the catalyst was filtered off and the solvent evaporated in vacuo to give 500 mg of the desired product (65%). MS m/z: 337.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06759420B1
Source datasetuspto-grants-2004_07
ORD IDord-dafdbf0dbb694e13bc2d3cb725d2cbbc
Source noteuspto-grants-2004_07