Water → HCID 178518718, compound

Participants

Reaction Steps

A mixture of 2-bromohypoxanthine (6 g, 28 mmol) and 2-piperidinoethylamine (7 ml, 56 mmol) in 2-methoxyethanol (30 ml) was heated to reflux overnight. The mixture was cooled to ambient temperature, giving rise to a yellow precipitate. Additional precipitate was generated on addition of water (50 ml). After stirring for 1 hour, the suspension was filtered and the solid obtained was washed with water and dried under vacuum to give the title compound (5.6 g). LC/MS SYSTEM C Rt=0.82 mins, m/z=263 MH+.

Provenance & Evidence