HCID 23508536, compound → HCID 23508516, compound

Participants

Reaction Steps

The procedure of Preparation Example 2 was repeated, except that 208 mg of N-(4′-methoxybiphenyl-2-yl)methanesulfonamide was used in place of 4′-methoxy-2-biphenylacetonitrile, and 1,2-dichloroethane was used in place of methylene chloride. The resulting crude product was purified by TLC (using a 2:1 mixture of hexane and ethyl acetate as the developing solvent) to obtain 178 mg of N-(4′-hydroxy-biphenyl-2-yl)methanesulfonamide.

Provenance & Evidence