HCID 23508390, compound → HCID 23508377, compound

Participants

Reaction Steps

The procedure of Preparation Example 2 was repeated, except that 63 mg of (2Z)-2-[4-(N-sulfamoylamino)phenyl]-3-(4-methoxyphenyl)-prop-2-enenitrile was used in place of 4′-methoxy-2-biphenylacetonitrile, and 1,2-dichloroethane was used in place of methylene chloride. The resulting crude product was purified by TLC (using a 2:1 mixture of chloroform and acetone as the developing solvent) to obtain 17 mg of (2Z)-2-[4-(sulfamoylamino)phenyl]-3-(4-hydroxyphenyl)prop-2-enenitrile.

Provenance & Evidence