Ethylamine → HCID 4719099, compound

HRID 1883770Notes

Reaction equation

HRID 1883770 reaction equation
[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH2:8]Br)=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH2:12]([NH2:14])[CH3:13]>C(O)C>[CH2:12]([NH:14][CH2:8][C:7]1[CH:10]=[CH:11][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=1)[CH3:13]

Participants

4

Reactant 2

HCID 6341EthylamineHCID 660114-Nitrobenzyl bromide

Product 1

HCID 4719099HCID 4719099, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

6.0 g of 4-nitrobenzyl bromide are dissolved in 25 ml of ethanol, combined with 25 ml of 10% ethanolic ethylamine solution and refluxed for 2 hours. Then the solution is concentrated by rotary evaporation, the residue is taken up with methylene chloride and washed with dilute sodium hydroxide solution. Finally the organic phase is evaporated down.

Workup

  1. temperaturerefluxed for 2 hours
  2. concentrationThen the solution is concentrated by rotary evaporation
  3. washwashed with dilute sodium hydroxide solution
  4. customFinally the organic phase is evaporated down

Sources & evidence

ORD record
ord-d60d15ae4e304301a742ad5b3111fd2e
Source dataset
uspto-grants-2004_07
Patent number
US06762180B1

Reaction notes

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