HRID1883798

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID3153997

4-(2,6-Dimethyl-piperidin-1-ylmethyl)-phenylamine

C14H22N2

结构：CCOC(=C1C(=O)N(C(C)=O)c2cc(C(=O)OC)ccc21)c1ccccc1

HCID66685972

未命名化合物

PRODUCTS

生成物

$结构：COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(CN2C(C)CCCC2C)cc1)c1ccccc1$

HCID178497139

未命名化合物

PROCEDURE

实验过程

Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone and 4-[(2,6-dimethyl-piperidin-1-yl)-methyl]-aniline Rf value: 0.5 (RP 8, methanol/five percent saline solution=4:1) C31H33N3O3

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ab897932ef2045ce974b204c1baa10be
来源数据集: uspto-grants-2004_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06762180B1
来源说明: uspto-grants-2004_07

反应 SMILES

C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=2)[C:6](=[C:17](OCC)[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:5]1=[O:27])(=O)C.[CH3:28][CH:29]1[CH2:34][CH2:33][CH2:32][CH:31]([CH3:35])[N:30]1[CH2:36][C:37]1[CH:43]=[CH:42][C:40]([NH2:41])=[CH:39][CH:38]=1>>[CH3:35][CH:31]1[CH2:32][CH2:33][CH2:34][CH:29]([CH3:28])[N:30]1[CH2:36][C:37]1[CH:38]=[CH:39][C:40]([NH:41]/[C:17](=[C:6]2\[C:5](=[O:27])[NH:4][C:12]3[C:7]\2=[CH:8][CH:9]=[C:10]([C:13]([O:15][CH3:16])=[O:14])[CH:11]=3)/[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[CH:42][CH:43]=1