Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1883798Generated: October 27, 2026

4-(2,6-Dimethyl-piperidin-1-ylmethyl)-phenylamine → methyl (3Z)-3-[[4-[(2,6-dimethylpiperidin-1-yl)methyl]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylate

https://huagongshe.com/reaction/1883798

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2,6-Dimethyl-piperidin-1-ylmethyl)-phenylamineHCID 3153997—
Reactant1-Acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinoneHCID 66685972—
Productmethyl (3Z)-3-[[4-[(2,6-dimethylpiperidin-1-yl)methyl]anilino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylateHCID 178497139—

Reaction Steps

Prepared from 1-acetyl-3-(1-ethoxy-1-phenylmethylene)-6-methoxycarbonyl-2-indolinone and 4-[(2,6-dimethyl-piperidin-1-yl)-methyl]-aniline Rf value: 0.5 (RP 8, methanol/five percent saline solution=4:1) C31H33N3O3

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06762180B1
Source datasetuspto-grants-2004_07
ORD IDord-ab897932ef2045ce974b204c1baa10be
Source noteuspto-grants-2004_07