Ammonium Hydroxide → HCID 9973158, compound

HRID 1884137Notes

Reaction equation

HRID 1884137 reaction equation
C[O:2][C:3](=O)[CH2:4][C:5]([NH:7][C:8]1[CH:13]=[CH:12][C:11]([O:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[C:18]([F:22])[CH:17]=2)=[CH:10][C:9]=1[OH:23])=[O:6].[OH-].[NH4+:26]>>[F:22][C:18]1[CH:17]=[C:16]([CH:21]=[CH:20][CH:19]=1)[CH2:15][O:14][C:11]1[CH:12]=[CH:13][C:8]([NH:7][C:5](=[O:6])[CH2:4][C:3]([NH2:26])=[O:2])=[C:9]([OH:23])[CH:10]=1

Participants

3

Reactant 2

HCID 14923Ammonium HydroxideHCID 69009976HCID 69009976, compound

Product 1

HCID 9973158HCID 9973158, compoundYield 23%

Procedure

Prepared in analogy to example 3 from N-[4-(3-fluoro-benzyloxy)-2-hydroxy-phenyl]-malonamic acid methyl ester and ammonium hydroxide. Yield=23%. Colorless solid. MS: m/e=319.4 (M++H).

Sources & evidence

ORD record
ord-e0499391624646d5b0d62f8827b1edb9
Source dataset
uspto-grants-2004_07
Patent number
US06762320B2

Reaction notes

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