Hydrochloric Acid → HCID 23508771, compound

Participants

Reaction Steps

3-{4-[4-(3,5-Bis-trifluoromethylphenyl)-2-(4-cyclohexylphenyl)-4-oxobutyryl]benzoylamino}propionic acid methyl ester (6.20 g, 9.38 mmol) was dissolved in THF (75 mL), HCl (6 N, 25 mL) was added and the mixture was heated to reflux, after 2 hours the heat was turned of and the mixture was stirred at room temperature for 16 hours. The mixture was evaporated to dryness to give the title compound. Yield: quantitative.

Provenance & Evidence