Methane → HCID 23707597, compound

Participants

Reaction Steps

Sodium hydroxide (1 M, 48 mL) was added to a solution in methanol (75 mL) of 3-[(4′-chloro[1,1′-biphenyl]-4-yl)sulfonyl]-2(RS)-[(phenylsulfanyl)-methyl]propanoic acid (20 g, obtained as described in Example 1). Charcoal was added and the mixture was filtered. Concentration of the filtrate to 1/3 of the original volume furnished a shiny precipitate, which was collected by filtration and sequentially washed with cold water, ethanol and diethyl ether. Drying to a constant weight provided 19 g of the title compound as white crystals.

Provenance & Evidence