HRID1884793

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1Cc2cc(OC)c(OC)cc2C[C@H]1C(=O)O.Cl

HCID54889

Moexipril hydrochloride

C27H35ClN2O7

HCID73981

未命名化合物

PRODUCTS

生成物

HCID5360315

Magnesium Chloride

Cl2Mg

结构：CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1Cc2cc(OC)c(OC)cc2C[C@H]1C(=O)O.[Mg]

HCID9958468

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID962

Water

H2O

PROCEDURE

实验过程

In the liquid mixture, the 10.0 g of moexipril hydrochloride reacted with 1.09 g of magnesium hydroxide to produce 9.53 g of moexipril magnesium plus 0.89 g of magnesium chloride, plus 0.67 g of water. The liquid was then filtered to remove the excess magnesium hydroxide.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-115ee7dae5f34681b42ebe4f8f71d28d
来源数据集: uspto-grants-2004_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06767556B2
来源说明: uspto-grants-2004_07

反应 SMILES

[CH3:1][CH2:2][O:3][C:4]([C@@H:6]([NH:15][C@H:16]([C:18]([N:20]1[C@H:29]([C:30]([OH:32])=[O:31])[CH2:28][C:27]2[CH:26]=[C:25]([O:33][CH3:34])[C:24]([O:35][CH3:36])=[CH:23][C:22]=2[CH2:21]1)=[O:19])[CH3:17])[CH2:7][CH2:8][C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1)=[O:5].[ClH:37].[OH-].[Mg+2:39].[OH-]>O>[CH3:1][CH2:2][O:3][C:4]([C@@H:6]([NH:15][C@H:16]([C:18]([N:20]1[C@H:29]([C:30]([OH:32])=[O:31])[CH2:28][C:27]2[CH:26]=[C:25]([O:33][CH3:34])[C:24]([O:35][CH3:36])=[CH:23][C:22]=2[CH2:21]1)=[O:19])[CH3:17])[CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:5].[Mg:39].[Cl-:37].[Mg+2:39].[Cl-:37]