Cyclododecane → Cyclododecanone

Participants

Reaction Conditions

Reaction Steps

Cyclododecane (1.66 g; 9.88 mmol), t-butylnitrite (2 mmol), N-hydroxyphthalimide (0.4 mmol), and acetic acid (2 ml) were placed in a flask and were stirred at 80° C. in an atmosphere of argon gas for 1 hour. The resulting reaction mixture was analyzed to find that cyclododecanone oxime, nitrosocyclododecane dimer, nitrocyclododecane, and cyclododecanone were formed in yields of 10%, 38%, 6%, and 3%, respectively.

Provenance & Evidence