HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178450490, compound → HCID 10331542, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178450490 | HCID 178450490 | — |
| Solvent | Diphenyl Ether | HCID 7583 | — |
| Product | HCID 10331542 | HCID 10331542 | 87.4% |
Reaction Steps
Ethyl 2-butyryl-3-(2-fluorophenylamino)acrylate (37 g, 0.13 mol) was added in portions to boiling diphenyl ether (450 ml), then heated at reflux for 1.5 hours. After partial cooling the mixture was diluted with petroleum ether (50 ml). Filtration and washing with petroleum ether gave 3-butyryl-8-fluoro-4(1H)-quinolone (26.5 g), m.p. 176°-178°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05143920 |
| Source dataset | uspto-grants-1992_09 |
| ORD ID | ord-a0536ca2ddb349c08dd7693a9add5878 |
| Source note | uspto-grants-1992_09 |