反应详情

Pivaloyl chloride (60 g) and malononitrile (33 g) were dissolved in methylene chloride (500 ml) and were placed in a flask equipped with a stirrer and a dropping funnel. Triethylamine (100 g) was added slowly with cooling over a period of 45 minutes. The triethylamine hydrochloride was removed and the filtrate was concentrated to about half volume. The solution was poured onto ice, acidified strongly with concentrated hydrochloric acid and the resulting product was filtered off and air dried.

1. customwere placed in a flask
2. customequipped with a stirrer and a dropping funnel
3. temperaturewith cooling over a period of 45 minutes
4. customThe triethylamine hydrochloride was removed
5. concentrationthe filtrate was concentrated to about half volume
6. additionThe solution was poured onto ice
7. filtrationthe resulting product was filtered off
8. customair dried