Oxalyl chloride → 4,4,4-Trifluorobutanoyl chloride

HRID 1885369Notes

Reaction equation

HRID 1885369 reaction equation
[F:1][C:2]([F:9])([F:8])[CH2:3][CH2:4][C:5](O)=[O:6].C(Cl)(=O)C([Cl:13])=O>C1C=CC=CC=1>[F:1][C:2]([F:9])([F:8])[CH2:3][CH2:4][C:5]([Cl:13])=[O:6]

Participants

4

Reactant 2

HCID 65578Oxalyl chlorideHCID 27770854,4,4-Trifluorobutanoic acid

Product 1

HCID 151044744,4,4-Trifluorobutanoyl chloride

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

4,4,4-Trifluorobutyric acid (5.8 g, 0.041 mole) was dissolved in benzene (30 ml). Oxalyl chloride (6.2 g, 0.049 mole) was added and the reaction stirred for 20 hrs. The benzene and excess oxalyl chloride was removed by distillation to give the title compound.

Workup

  1. customThe benzene and excess oxalyl chloride was removed by distillation

Sources & evidence

ORD record
ord-49a422d614774f65b2a81dd012721ec5
Source dataset
uspto-grants-1992_09
Patent number
US05144037

Reaction notes

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