HRID1885440

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1ccccc1C(OC(C)=O)(c1ccccc1OC)[C@@H](N)CC(C)C

HCID18638008

未命名化合物

结构：CC(C)[C@H](N)C(O)(c1ccccc1)c1ccccc1.Cl

HCID18638009

(2S)-2-Amino-3-methyl-1,1-diphenylbutan-1-ol--hydrogen chloride (1/1)

C17H22ClNO

结构：CC(=O)OC(c1ccccc1)(c1ccccc1)[C@H](N)Cc1ccccc1

HCID54165093

未命名化合物

HCID67707196

未命名化合物

PRODUCTS

生成物

$结构：CC(C)(C)C(O)/C(=C\c1ccc(Cl)cc1)n1cncn1$

HCID6436604

(E)-1-(4-Chlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)-1-penten-3-ol

C15H18ClN3O

PROCEDURE

实验过程

Reaction was carried out according to Example 1 using (S)-2-amino-1,1-diphenylpropan-1-ol hydrochloride, (S)-2-amino-1,1-diphenyl-3-methylbutan-1-ol hydrochloride, (R)-2-amino-1,1-diphenyl-3-phenylpropan-1-ol acetate and (S)-2-amino-1,1-di-(2'-methoxyphenyl)-4-methylpentan-1-ol acetate in place of (S)-2-amino-1,1-diphenyl-4-methylpentan-1-ol hydrochloride, to obtain the (+)-isomer and (-)-isomer of (E)-1-(4-chlorophenyl)-2-(1,2,4-triazol-1-yl)-4,4-dimethyl-1-penten-3-ol. The results obtained were summarized in Table 1.

WORKUP

后处理

customReaction