Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | HCID 19878629 | HCID 19878629 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 67895273 | HCID 67895273 | — |
Reaction Steps
0.24 mole (23 ml) of acetic anhydride is added dropwise to a solution of 0.24 mole (72 g) of 5-amino-2-[N-benzyloxycarbonyl-N-(β-hydroxyethyl)amino]phenol in one liter of ethyl acetate heated to 80° C. After evaporation of the solvent under vacuum, the expected product is purified on a silica column. It then melts at 72° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05145483 |
|---|
| Source dataset | uspto-grants-1992_09 |
|---|
| ORD ID | ord-eddfb0975ae34807b219d0c1fa92d54d |
|---|
| Source note | uspto-grants-1992_09 |
|---|
