Hydrochloric Acid → Ethyl 3-ethoxy-3-iminopropionate hydrochloride

HRID 1885542Notes

Reaction equation

HRID 1885542 reaction equation
[ClH:1].[C:2]([CH2:4][C:5]([O:7][CH2:8][CH3:9])=[O:6])#[N:3].[CH3:10][CH2:11][O:12]CC>C(O)C>[ClH:1].[CH2:8]([O:7][C:5]([CH2:4][C:2](=[NH:3])[O:12][CH2:11][CH3:10])=[O:6])[CH3:9]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 7764Ethyl cyanoacetate

Product 1

HCID 75345Ethyl 3-ethoxy-3-iminopropionate hydrochloride

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Hydrochloric acid gas is passed at 0°-10° C. into a solution of 678 g (6 mol) of ethyl cyanoacetate in 400 ml of ethanol and 3 1 of ether for 7 h, the mixture is allowed to stand overnight at 25° C., and the deposited solid is filtered off with suction and dried in vacuo.

Workup

  1. filtrationthe deposited solid is filtered off with suction
  2. customdried in vacuo

Sources & evidence

ORD record
ord-eea8a8eaf12f4188b6a9b9cfeabf895a
Source dataset
uspto-grants-1992_09
Patent number
US05145857

Reaction notes

Loading…