2-Benzoxazolinone, 3-methyl- → 3-Methyl-6-(pyridine-3-carbonyl)-1,3-benzoxazol-2(3H)-one

HRID 1885891Notes

Reaction equation

HRID 1885891 reaction equation
[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][C:3]1=[O:11].Cl.[C:13](Cl)(=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[N:16][CH:15]=1>>[CH3:1][N:2]1[C:6]2[CH:7]=[CH:8][C:9]([C:13](=[O:20])[C:14]3[CH:19]=[CH:18][CH:17]=[N:16][CH:15]=3)=[CH:10][C:5]=2[O:4][C:3]1=[O:11]

Participants

3

Reactant 2

HCID 308462-Benzoxazolinone, 3-methyl-HCID 884383-Pyridinecarbonyl chloride, hydrochloride (1:1)

Product 1

HCID 151714393-Methyl-6-(pyridine-3-carbonyl)-1,3-benzoxazol-2(3H)-one

Procedure

The flask is equipped with a reflux condenser and taken to an oil bath at a temperature in the region of 45° C. 6 g (0.04 mol) of 3-methylbenzoxazolinone and 10.6 g (0.06 mol) of nicotinoyl chloride hydrochloride are introduced.

Workup

  1. customThe flask is equipped with a reflux condenser
  2. customtaken to an oil bath at a temperature in the region of 45° C

Sources & evidence

ORD record
ord-7240b55f14fc490aa589981bb11f01fd
Source dataset
uspto-grants-1992_09
Patent number
US05147883

Reaction notes

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