Hydrochloric Acid → HCID 67904724, compound

Participants

Reaction Conditions

Reaction Steps

The compound of Example 1 (1.4 g) was dissolved in methanol:water (2:1, 10 ml) and to the stirred solution was added lithium hydroxide (0.267 g). The resulting mixture was maintained at 45° C. for one hour. The pH was adjusted to 5.0 with 2N HCl, water (50 ml) was added and the product was extracted into chloroform (50 ml). After drying over anhy. sodium sulphate, the mixture was filtered and the filtrate concentrated in vacuo to give the desired product (1.15 g).

Provenance & Evidence