Potassium Carbonate → HCID 19876584, compound

HRID 1885976Notes

Reaction equation

HRID 1885976 reaction equation
[Cl:1][C:2]1[C:7]([C:8](OC2C=CC([N+]([O-])=O)=CC=2)=[O:9])=[C:6]([NH:20][C:21]2[N:26]=[C:25]([O:27][CH3:28])[CH:24]=[C:23]([O:29][CH3:30])[N:22]=2)[CH:5]=[CH:4][CH:3]=1.[CH3:31][S:32]([NH2:35])(=[O:34])=[O:33].C(=O)([O-])[O-].[K+].[K+]>C(#N)C>[Cl:1][C:2]1[C:7]([C:8]([NH:35][S:32]([CH3:31])(=[O:34])=[O:33])=[O:9])=[C:6]([NH:20][C:21]2[N:26]=[C:25]([O:27][CH3:28])[CH:24]=[C:23]([O:29][CH3:30])[N:22]=2)[CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 72879MethanesulfonamideHCID 19876593HCID 19876593, compound

Product 1

HCID 19876584HCID 19876584, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

This compound is prepared in a manner analogous to that of Example 1, Step I, using equimolar amounts of 4-nitrophenyl 6-chloro-2-(4,6-dimethoxypyrimidin-2-ylamino)benzoate, methanesulfonamide, and potassium carbonate in acetonitrile, yielding 2-[3-chloro-2-(methylsulfonylaminocarbonyl)phenylamino]-4,6-dimethoxypyrimidine, Compound 39 of Table 1.

Workup

  1. customThis compound is prepared in a manner analogous to that of Example 1, Step I

Sources & evidence

ORD record
ord-7194868774e9402ba4ac5c0c4b9c9e3a
Source dataset
uspto-grants-1992_09
Patent number
US05149357

Reaction notes

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