HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetoacetate → 2-Ethoxycarbonyl-3-phenylcyclohex-5-enone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Reactant | Cinnamaldehyde | HCID 637511 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Catalyst | Ethyl Acetoacetate | HCID 8868 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Ethoxycarbonyl-3-phenylcyclohex-5-enone | HCID 15581449 | 100% |
Reaction Steps
The reaction was repeated replacing the sodium metal with ethyl acetoacetate, sodium salt. Thus, 12.6 grams (0.097 mole) of ethyl acetoacetate, 0.5 gram (0.003 mole) of ethyl acetoacetate, sodium salt and 13.2 grams (0.100 mole) of trans-cinnamaldehyde in 50 mL of ethanol were reacted in a manner analogous to that of Example 6, Step A. A 100% yield (24.4 grams) of 2-ethoxycarbonyl-3-phenylcyclohex-5-enone was assumed.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05149357 |
| Source dataset | uspto-grants-1992_09 |
| ORD ID | ord-545240a51ca748aba1adbeb7c5b90282 |
| Source note | uspto-grants-1992_09 |