HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 3-Nitrobenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Benzoyl chloride, 3-nitro- | HCID 8495 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-Nitrobenzoic acid | HCID 8497 | — |
Reaction Steps
1 liter water and 60 g NaOH are added to 100 g Vulkadur RB® and a solution of 200 g 3-nitrobenzoyl chloride in 300 ml THF is then added with stirring (cooling with ice). After 174 h, 500 ml CH2Cl2 are added and the organic phase is separated off and concentrated by evaporation. The N content of the product corresponds to the theoretical.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05149728 |
| Source dataset | uspto-grants-1992_09 |
| ORD ID | ord-9571bcf9ec434a7d835042cf1326a8a9 |
| Source note | uspto-grants-1992_09 |