Water → 3-Nitrobenzoic acid

HRID 1886100Notes

Reaction equation

HRID 1886100 reaction equation
[OH2:1].[OH-].[Na+].[N+:4]([C:7]1[CH:8]=[C:9]([CH:13]=[CH:14][CH:15]=1)[C:10](Cl)=[O:11])([O-:6])=[O:5].C(Cl)Cl>C1COCC1>[N+:4]([C:7]1[CH:8]=[C:9]([CH:13]=[CH:14][CH:15]=1)[C:10]([OH:1])=[O:11])([O-:6])=[O:5]

Participants

6

Reactant 4

HCID 962WaterHCID 6344DichloromethaneHCID 8495Benzoyl chloride, 3-nitro-HCID 14798Sodium Hydroxide

Product 1

HCID 84973-Nitrobenzoic acid

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

1 liter water and 60 g NaOH are added to 100 g Vulkadur RB® and a solution of 200 g 3-nitrobenzoyl chloride in 300 ml THF is then added with stirring (cooling with ice). After 174 h, 500 ml CH2Cl2 are added and the organic phase is separated off and concentrated by evaporation. The N content of the product corresponds to the theoretical.

Workup

  1. temperature(cooling with ice)
  2. customthe organic phase is separated off
  3. concentrationconcentrated by evaporation

Sources & evidence

ORD record
ord-9571bcf9ec434a7d835042cf1326a8a9
Source dataset
uspto-grants-1992_09
Patent number
US05149728

Reaction notes

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