Triphenylphosphine → HCID 21616535, compound

HRID 1886116Notes

Reaction equation

[F:1][C:2]([F:21])([F:20])[C:3]([C:5]1[CH:15]=[CH:14][C:8]([O:9][CH2:10][CH2:11][CH2:12][Br:13])=[C:7]([CH2:16][CH2:17][CH3:18])[C:6]=1[OH:19])=[O:4].[C:22]1([P:28]([C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=2)[C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[Br-:13].[F:1][C:2]([F:21])([F:20])[C:3]([C:5]1[CH:15]=[CH:14][C:8]([O:9][CH2:10][CH2:11][CH2:12][P+:28]([C:29]2[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=2)([C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=2)[C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=2)=[C:7]([CH2:16][CH2:17][CH3:18])[C:6]=1[OH:19])=[O:4]

Participants

Reactant 2

HCID 11776Triphenylphosphine

HCID 19876974HCID 19876974, compound

Product 1

HCID 21616535HCID 21616535, compound

Procedure

The title compound is prepared analogously to Example 1c) from 3-(4-trifluoroacetyl-3-hydroxy-2-propylphenoxy)-propyl bromide and triphenylphosphine; m.p. 170°-190° C.

Sources & evidence

ORD record: ord-1bf0dc126a064970a22565a897817790
Source dataset: uspto-grants-1992_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05149717

Reaction notes

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