反应详情

A solution of 0.2 g of CuCl and 0.5 g of hydroxylammonium hydrochloride in 16 ml of 50% aqueous ethylamine is added to a solution of 0.1 m of 4-fluorophenylacetylene in 100 ml of methanol. 0.1 m of p-n-pentylphenylbromoethyne dissolved in methanol is added dropwise under a nitrogen atmosphere and with stirring, the mixture is stirred for one hour, diluted with water and extracted with ether, and the extracts are washed until neutral. Customary work-up gives 1-p-n-pentylphenyl-4-p-fluorophenylbutadiyne.

1. additionis added dropwise under a nitrogen atmosphere
2. stirringthe mixture is stirred for one hour
3. extractionextracted with ether
4. washthe extracts are washed until neutral