HCID 586491, compound → HCID 136072584, compound

HRID 1886321Notes

Reaction equation

HRID 1886321 reaction equation
[OH:1][C:2]1[CH:7]=[C:6]([OH:8])[CH:5]=[CH:4][C:3]=1[C:9](=O)[CH2:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.[NH2:19][C:20]1[CH:25]=[CH:24][C:23]([C:26]2[CH2:27][CH2:28][C:29](=[O:32])[NH:30][N:31]=2)=[CH:22][CH:21]=1>C(OCC)(=O)C>[OH:1][C:2]1[CH:7]=[C:6]([OH:8])[CH:5]=[CH:4][C:3]=1[C:9](=[N:19][C:20]1[CH:25]=[CH:24][C:23]([C:26]2[CH2:27][CH2:28][C:29](=[O:32])[NH:30][N:31]=2)=[CH:22][CH:21]=1)[CH2:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

4

Reactant 2

HCID 586491HCID 586491, compoundHCID 6767506-(4-Aminophenyl)-4,5-dihydropyridazin-3(2H)-one

Product 1

HCID 136072584HCID 136072584, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Conditions

Temperature
190 °C

Procedure

A mixture containing 1.45 g of 1-(2,4-dihydroxyphenyl)3-phenyl-propan-1-one and 6-(4-aminophenyl)-4,5-dihydropyridazin-3(2H)one was heated for 72 h at 190° C. The product was treated with ethyl acetate, yield 0.37 g (16%), m.p. 208°-210° C.

Sources & evidence

ORD record
ord-e1371ab111fa4c4088a4ae61b733b59a
Source dataset
uspto-grants-1992_09
Patent number
US05151420

Reaction notes

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